| drug details | | 1 | | name | Tetracycline | | classification | Tetracycline antibiotic | | pharmacokinetics | Tetracycline is absorbed from the gastrointestinal tract. Peak plasma concentrations are typically reached within 1-4 hours after oral administration. It is distributed throughout various tissues and organs, including the bone and teeth. Renal excretion is the primary route of elimination, with some biliary excretion occurring as well. Absorption is significantly reduced by food, and it can chelate with calcium, magnesium, and iron in the gastrointestinal tract, reducing its absorption. | | suggested dosage | Dosage varies depending on the specific infection and patient condition. A typical adult dose for bacterial infections is 250-500 mg every 6 hours. Consult a healthcare professional for the appropriate dosage. | | indications | Treatment of various bacterial infections, including skin infections, respiratory infections, urinary tract infections, and sexually transmitted infections. It can also be used for acne treatment in some cases. | | safety in pregnancy | Tetracycline is generally not recommended during pregnancy, particularly in the first trimester, due to potential adverse effects on developing teeth and bones. Consult with a physician before using during pregnancy. | | safety in breastfeeding | Tetracycline may be excreted in breast milk. It is generally not recommended to use during breastfeeding due to possible adverse effects on the infant. Consult a doctor. | | side effects | Common side effects include nausea, vomiting, diarrhea, abdominal pain, and stomach upset. More serious side effects may include photosensitivity (increased sensitivity to sunlight), allergic reactions, and potentially permanent discoloration of developing teeth in children and adolescents. The risk of liver problems, kidney damage, and heart problems is rare but possible. | | alternatives | | | contraindications | Patients with known hypersensitivity to tetracycline or other related antibiotics. Pregnant women in the first trimester. Use with caution in patients with kidney or liver impairment. | | interactions | Tetracycline can interact with antacids, calcium supplements, iron supplements, and some other antibiotics. Specific interactions vary depending on the interacting medication. Consult a healthcare professional about any potential interactions with other medications. | | warnings and precautions | Avoid sunlight or tanning beds. If you experience any unusual symptoms, stop taking the medication and consult a doctor. Patients with a history of allergies, or with pre-existing liver/kidney problems need close monitoring. | | additional informations | Tetracycline should be taken on an empty stomach to maximize absorption, at least 1 hour before or 2 hours after meals or other medications. | | patient details | |
| | 2 | | name | Erythromycin | | classification | Macrolide antibiotic | | pharmacokinetics | Erythromycin is absorbed from the gastrointestinal tract, with peak plasma concentrations usually reached within 1-4 hours after oral administration. Food can impact absorption and distribution. The primary route of elimination is through the liver, with some excretion in the kidneys. Different formulations, like intravenous or topical, have varying pharmacokinetic profiles. | | suggested dosage | Dosage depends on the specific infection and the patient's condition. A typical oral dosage for bacterial infections is 250-500 mg every 6 hours. Consult a physician for the correct dosage. | | indications | Treatment of various bacterial infections. Also used for certain types of pneumonia. | | safety in pregnancy | Consult a physician before using during pregnancy due to potential risks. May be a safer choice than tetracyclines in certain circumstances. | | safety in breastfeeding | Erythromycin may be excreted in breast milk. Consult a physician before using during breastfeeding. | | side effects | Common side effects include nausea, vomiting, diarrhea, and abdominal discomfort. More severe side effects may include allergic reactions. Consult a doctor about possible interactions or side effects for individual cases. | | alternatives | | | contraindications | Patients with known hypersensitivity to erythromycin or other macrolides. | | interactions | Erythromycin can interact with certain medications, including some drugs that affect the liver or the heart. Consult a healthcare professional about potential interactions with other medications. | | warnings and precautions | If you experience severe or persistent side effects, stop taking the medication and consult a doctor. Monitor for possible liver issues. | | additional informations | Erythromycin can be taken with or without food, but consistency throughout the day improves absorption. | | patient details | |
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