Anticholinergics

Drug Overview

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drug details
nameAnticholinergics
classificationVarious; including, but not limited to, muscarinic receptor antagonists, antispasmodics, and some antidepressants.
pharmacokineticsPharmacokinetic properties vary significantly between anticholinergic drugs. Absorption varies; some are well-absorbed orally, while others are administered intravenously or topically. Distribution depends on drug properties (water or lipid solubility). Metabolism and excretion also vary, with some metabolized in the liver, others in the kidneys, and elimination half-lives ranging from hours to days.
suggested dosageDosage varies widely based on the specific drug, patient condition, and route of administration. Always consult a healthcare professional for appropriate dosage recommendations.
indicationsUses vary depending on the specific anticholinergic medication. General uses include treating Parkinson's disease symptoms, managing overactive bladder, reducing spasms (e.g., gastrointestinal), treating certain poisonings, and managing pre-operative/intraoperative conditions.
safety in pregnancyAnticholinergic use during pregnancy requires careful consideration and consultation with a healthcare professional. Some anticholinergics may have adverse effects on the developing fetus. Avoid if possible, and carefully weigh potential benefits against risks.
safety in breastfeedingAnticholinergics may pass into breast milk, potentially affecting the nursing infant. Consult a healthcare provider to assess the risk-benefit ratio.
side effectsCommon side effects include dry mouth, blurred vision, constipation, urinary retention, difficulty urinating, tachycardia, difficulty swallowing, cognitive impairment, confusion, hallucinations, dizziness, and altered mental status.
alternatives
1
drug nameIpratropium
alternative classMuscarinic Cholinergic Antagonists (lung conditions)
2
drug nameOxybutynin
alternative classAntimuscarinics (overactive bladder)
3
drug nameHyoscyamine
alternative classAntispasmodics (IBS)
contraindicationsContraindications vary by specific drug. Examples include narrow-angle glaucoma, urinary retention, gastrointestinal tract obstruction, certain heart conditions, seizure history, and hypersensitivity to the drug.
interactionsMany drugs interact with anticholinergics. This includes other medications with anticholinergic properties or those affecting liver/kidney function, potentially altering anticholinergic metabolism/excretion and requiring dosage adjustments. Always inform your physician of all medications taken.
warnings and precautionsIncreased risk of side effects in older adults and patients with pre-existing conditions. Carefully monitor vital signs (e.g., heart rate, blood pressure, mental status).
additional informationsPatient age and weight are not directly relevant for general dosage recommendations. Specific dosages and drug selection must be individualized by a physician considering patient history, current health conditions, other medications, and potential interactions.
important notesThis is a general overview. Consult a physician for personalized advice on anticholinergic use.

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Reference Patient:(25 years,Male, 70KGs) *Not a medical advice

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