| name | Benzoyl Peroxide |
| classification | Antimicrobial, Comedolytic |
| pharmacokinetics | Benzoyl peroxide is primarily metabolized in the liver. It is absorbed through the skin and broken down into inactive metabolites. Excretion is primarily through the urine. The exact pharmacokinetic properties can vary based on concentration and skin penetration. Topical application is the primary route. |
| suggested dosage | | initial | 2.5% concentration, once daily | | titration | May increase to 5% or 10% concentration, once or twice daily as tolerated and directed by healthcare professional. | | additional notes | Specific dosage and frequency will vary based on severity of acne and individual patient response. |
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| indications | Treatment of mild to moderate acne vulgaris. Effective in reducing comedones, inflammation, and erythema. |
| safety in pregnancy | | statement | Limited data available. Use only if the potential benefit outweighs the potential risk to the fetus. Consult with a healthcare professional. | | additional notes | Risk assessment should consider the specific stage of pregnancy and other health factors. |
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| safety in breastfeeding | | statement | Limited data available. Use only if the potential benefit outweighs the potential risk to the infant. Consult with a healthcare professional. | | additional notes | Monitor for any potential adverse effects in the infant. |
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| side effects | | 1 | | category | common | | effects | | 1 | Skin irritation | | 2 | dryness | | 3 | redness | | 4 | burning | | 5 | peeling | | 6 | itching |
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| | 2 | | category | less_common | | effects | | 1 | Allergic reactions | | 2 | contact dermatitis |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to benzoyl peroxide or other ingredients in the formulation | | 2 | Avoid contact with eyes |
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| interactions | | 1 | | type | potential_reduction_in_effectiveness | | description | Potentially less effective when used with other topical acne treatments that are also comedolytic. |
| | 2 | | type | increased_photosensitivity | | description | May increase the sensitivity of the skin to sunlight. Use with caution during exposure. |
| | 3 | | type | other_medications | | description | Consider potential interaction with other medications the patient might be taking. |
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| warnings and precautions | | 1 | Avoid contact with eyes. | | 2 | Discontinue use if irritation or allergic reaction occurs. | | 3 | Patients with sensitive skin may experience more frequent or severe side effects. | | 4 | Monitor skin for adverse reactions and adjust treatment as needed. | | 5 | Use caution in patients with compromised skin barrier function. |
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| additional informations | | 1 | Benzoyl peroxide can bleach fabrics and hair. | | 2 | Apply a thin layer and avoid excessive use, as this could worsen side effects. | | 3 | Follow prescribed regimen and monitor the patient for adverse reactions. |
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| patient specific considerations | | age | 25 years | | weight | 70 kg | | dosage notes | Dosage recommendations remain within typical ranges. Individualized treatment will be necessary for tailoring the frequency and concentration based on the patient's response to the treatment. |
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