| drug name | Clobetasol Propionate Topical Cream |
| classification | Corticosteroid, potent topical |
| pharmacokinetics | Clobetasol propionate is a potent corticosteroid that is primarily absorbed through the skin. The exact pharmacokinetic parameters are not clearly defined for topical use, as absorption varies greatly based on the area treated, the thickness of the skin, and the duration of application. It is believed that minimal systemic absorption occurs with proper use, although prolonged or excessive use can lead to systemic effects. |
| suggested dosage | Apply a thin film of cream to the affected area(s) once or twice daily. Follow your dermatologist's instructions. Do not apply to large areas of skin, and do not use for longer than prescribed. |
| indications | Used to treat inflammatory skin conditions such as eczema, psoriasis, and other dermatoses. Can also be used for various skin rashes and localized inflammatory conditions. |
| safety in pregnancy | Use during pregnancy only if the potential benefit justifies the potential risk. Consult with your doctor. |
| safety in breastfeeding | Limited data are available on the safety of clobetasol propionate topical cream in breastfeeding mothers. Consult your physician before use. |
| side effects | | 1 | Local skin reactions such as burning, itching, irritation, redness, or dryness. | | 2 | Skin thinning (atrophy) | | 3 | Striae (stretch marks) | | 4 | Telangiectasia (small dilated blood vessels) | | 5 | Acneiform eruptions | | 6 | Skin depigmentation (loss of color) | | 7 | Infection at the application site | | 8 | Systemic effects (rare with proper use) including Cushing's syndrome-like symptoms, elevated blood sugar, and adrenal suppression. |
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| contraindications | | 1 | Known hypersensitivity or allergy to clobetasol propionate or other corticosteroids. | | 2 | Active skin infections at the application site | | 3 | Ocular use |
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| interactions | Limited interactions are known, but inform your doctor about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, to avoid potential interactions. |
| warnings and precautions | | 1 | Avoid contact with the eyes. | | 2 | Do not use on large areas of skin, or use for prolonged periods without consulting a physician | | 3 | Patients with a history of skin thinning, or other skin conditions should use with caution. | | 4 | Stop use and contact your physician if symptoms worsen or do not improve. | | 5 | Use only as directed by a healthcare professional. | | 6 | Monitor for signs of systemic effects. |
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| additional information | This information is for general knowledge and does not constitute medical advice. Always consult a dermatologist or other qualified healthcare provider before using any topical medication, especially for prolonged use or in conditions involving large areas of skin. |
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