| name | DMPA (Depot Medroxyprogesterone Acetate) |
| classification | Progestin-only injectable contraceptive |
| pharmacokinetics | DMPA is administered intramuscularly or subcutaneously. It is slowly released into the bloodstream, maintaining a steady hormonal level. The primary active metabolite is medroxyprogesterone. The drug's elimination half-life is relatively long, typically several weeks, which contributes to its effectiveness and its contraceptive properties. |
| suggested dosage | DMPA is typically administered as a 150 mg intramuscular or subcutaneous injection every 3 months. Dosage varies slightly based on specific product formulations. |
| indications | Primary use is as a highly effective method of contraception. |
| safety in pregnancy | DMPA is **contraindicated** during pregnancy. Pregnant women should not use DMPA. |
| safety in breastfeeding | DMPA use may affect breast milk production. Consult with a healthcare professional to determine if DMPA is suitable. Some studies suggest no significant negative effects on breastfeeding. |
| side effects | | 1 | Weight changes (gain or loss) | | 2 | Mood changes (e.g., irritability) | | 3 | Headache | | 4 | Irregular bleeding (spotting, breakthrough bleeding) | | 5 | Breast tenderness | | 6 | Decreased bone mineral density (potential long-term effect, particularly if used for prolonged periods) | | 7 | Acne | | 8 | Hair loss | | 9 | Nausea | | 10 | Fatigue |
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| alternatives | |
| contraindications | | 1 | Known or suspected pregnancy | | 2 | Allergy to DMPA or any of its components | | 3 | Severe liver disease | | 4 | Breast cancer or a history of it |
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| interactions | | 1 | Potential interaction with some medications (e.g., anticonvulsants). | | 2 | DMPA can alter the metabolism of other medications. | | 3 | Always inform your doctor of all medications you're taking |
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| warnings and precautions | | 1 | DMPA use can cause significant changes in bone mineral density, which may be reversible with discontinuation of the drug but the long-term impact is not fully understood | | 2 | Use is not recommended for women with a history of blood clots | | 3 | Regular check-ups with a healthcare professional are important | | 4 | DMPA does not protect against sexually transmitted infections (STIs) | | 5 | Delay in return of fertility after cessation of DMPA. |
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| additional informations | DMPA should only be used with careful consideration by a qualified healthcare provider. It is a potent contraceptive and its impact on the body may require ongoing monitoring and management. |
| patient specific details | | age | 25 | | weight | 70 | | gender | male | | note | DMPA is not appropriate for male patients. This information is not applicable to the patient's gender. |
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