| drug name | Ergocalciferol |
| classification | Vitamin D2 |
| pharmacokinetics | Ergocalciferol is absorbed in the small intestine. Its primary form of metabolism is via 25-hydroxylation in the liver, and subsequently 1-hydroxylation in the kidney to form the active metabolite 1,25-dihydroxyvitamin D. The half-life of ergocalciferol is variable but is generally several weeks. |
| suggested dosage | | adult | | general | Dosage for ergocalciferol varies greatly depending on the indication. Consult a healthcare professional for appropriate dosing based on individual needs. | | specific examples | | 1 | | indication | Vitamin D deficiency prevention | | dosage range | 400-800 IU daily |
| | 2 | | indication | Vitamin D deficiency treatment | | dosage range | 50,000-100,000 IU weekly for a few weeks, followed by a maintenance dose |
| | 3 | | indication | Rickets | | dosage range | 10,000 IU to 50,000 IU daily, adjusted per physician’s recommendation |
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| | patient specific | Dosage must be determined by a healthcare professional taking into consideration the patient's specific needs and medical history, including any concurrent medications. |
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| indications | Ergocalciferol is used to prevent and treat vitamin D deficiency. This deficiency can lead to conditions like rickets in children, and osteomalacia or osteoporosis in adults. It is also used to treat conditions resulting from vitamin D insufficiency. |
| safety in pregnancy | Ergocalciferol is generally considered safe during pregnancy when used within the recommended dosage range. However, it is crucial to follow the advice of a healthcare professional. High doses can potentially cause hypercalcemia in the mother and fetus. |
| safety in breastfeeding | Ergocalciferol is considered safe for use during breastfeeding when administered in the recommended doses. However, consult a doctor for the appropriate dosage. |
| side effects | | 1 | Hypercalcemia (high calcium levels in the blood) | | 2 | Nausea | | 3 | Vomiting | | 4 | Loss of appetite | | 5 | Headache | | 6 | Constipation | | 7 | Increased thirst and urination | | 8 | Kidney stones |
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| contraindications | | 1 | Hypercalcemia or hypercalciuria | | 2 | Patients with kidney disease, especially with impaired renal function. | | 3 | Known hypersensitivity to vitamin D. |
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| interactions | Ergocalciferol may interact with certain medications such as thiazide diuretics, corticosteroids, and certain anti-acids. Inform your doctor about all medications you are currently taking. |
| warnings and precautions | Monitor blood calcium levels during treatment. Avoid exceeding recommended dosages without medical supervision. Important: Always consult a physician before using ergocalciferol, especially if you have any underlying health conditions. |
| additional informations | Ergocalciferol is a fat-soluble vitamin, meaning it is absorbed and stored in the body. It is essential for calcium absorption and bone health. Dietary intake of vitamin D rich foods is also important for maintaining adequate levels of vitamin D. |
| patient specific details | A 25-year-old male weighing 70 kg may require different dosages compared to a patient with different demographics or conditions, particularly if other issues, like dietary habits, are involved. A healthcare professional should provide tailored recommendations and monitoring. |
