| name | Hydrocortisone Ointment (lower potency) |
| classification | Corticosteroid Topical |
| pharmacokinetics | Hydrocortisone, when applied topically, is primarily absorbed locally. Systemic absorption is generally minimal with lower potency preparations. The extent of absorption depends on factors including the vehicle, the duration of application, and the integrity of the skin. The drug is metabolized primarily in the liver and excreted in the urine and bile. |
| suggested dosage | Apply a thin film of ointment to the affected area 1-4 times daily, as directed by a physician. Do not apply more frequently than directed and do not increase the amount or duration of use without consulting a doctor. Dosage will depend on the severity and location of the skin condition being treated. |
| indications | | 1 | Mild to moderate inflammatory skin conditions such as eczema, contact dermatitis, and pruritus (itching). | | 2 | Mild to moderate skin conditions like intertrigo or diaper rash. | | 3 | Prevention of recurrence in some skin conditions when used as prescribed | | 4 | Some inflammatory conditions of the scalp (e.g., seborrheic dermatitis) may also be treated with topical hydrocortisone. |
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| safety in pregnancy | Hydrocortisone ointment, used topically at lower potencies, is generally considered safe for use during pregnancy. However, it's essential to use the lowest effective dose for the shortest duration possible and to follow the advice of your doctor, especially during the first trimester. |
| safety in breastfeeding | Lower potency hydrocortisone ointment is generally considered safe for use during breastfeeding when applied topically to the affected skin. However, avoid contact with breast tissue and consult with your physician for guidance. As with pregnancy, the lowest effective dose and shortest duration are preferred. |
| side effects | | 1 | Skin irritation, redness, or dryness at the application site. | | 2 | Local burning sensation. | | 3 | Rarely, systemic side effects like Cushing's syndrome or adrenal suppression can occur if absorption is excessive. | | 4 | Skin thinning (atrophy) or stretch marks (striae) at the application site, especially with prolonged high-frequency use of potent preparations. |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to hydrocortisone or any other ingredients in the product. | | 2 | Use on open wounds or infected skin (consult a doctor). | | 3 | Use over large areas of skin for prolonged periods without professional advice | | 4 | Use on children without consultation with pediatrician |
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| interactions | While rare, topical hydrocortisone may interact with other topical medications. Consult with your physician if using other topical treatments. No significant drug interactions with oral medications are expected. |
| warnings and precautions | | 1 | Do not use on the face or other sensitive areas without consultation from a dermatologist. | | 2 | Avoid contact with eyes. If contact occurs, rinse thoroughly with water. | | 3 | If symptoms worsen or do not improve, discontinue use and consult a physician immediately. | | 4 | Do not use hydrocortisone ointment for fungal infections. |
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| additional informations | | 1 | The patient's age and weight are generally not critical factors for dosage adjustments of topical hydrocortisone, though local skin condition is paramount. | | 2 | Always use as directed and follow the instructions provided with the medication. | | 3 | If the patient is on other medications, it's crucial to inform the physician before starting hydrocortisone ointment. |
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