Inhaled Corticosteroid And Long Acting Beta2 Agonist

Drug Overview

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drug details
1
drug classInhaled Corticosteroids
general information
classificationAnti-inflammatory, inhaled corticosteroids
pharmacokineticsSystemic absorption is minimal when used as directed. Inhaled corticosteroids are primarily delivered to the lungs and exert their therapeutic effects locally. Absorption into the bloodstream is significantly reduced compared to oral or intravenous routes. Metabolism primarily occurs in the liver, with varying half-lives depending on the specific medication.
safety in pregnancyUse during pregnancy should be carefully considered and monitored by a physician. Potential risks and benefits must be weighed. Some inhaled corticosteroids may cross the placenta. More research is needed to fully understand the potential long-term effects on the developing fetus.
safety in breastfeedingLimited data exists on the safety of inhaled corticosteroids in breastfeeding mothers. Generally, low doses are considered safe; however, the potential effects on the infant should be discussed with a physician and potential risks must be weighed against the need for therapy.
additional informationsThis information is for educational purposes only and should not be considered medical advice. Consult a physician for proper diagnosis and treatment. Always follow your doctor's instructions regarding dosage, frequency, and administration.
specific medications
1
nameFluticasone
dosage and administrationSpecific dosage varies by patient. Consult your physician.
indicationsTreatment and prevention of asthma exacerbations and symptoms; maintenance therapy for chronic asthma; treatment of allergic rhinitis; other inflammatory conditions of the airways.
side effects
1Oral candidiasis (thrush)
2Hoarseness
3Cough
4Headache
5Nasal irritation
6Dysphonia
7Oropharyngeal irritation
8Systemic effects (e.g., adrenal suppression) are rare with inhaled doses but can occur with high doses or prolonged use.
contraindicationsHypersensitivity to Fluticasone or its components; active systemic fungal infections of the mouth or throat; severe respiratory infections.
interactionsPossible interactions with other medications may occur. The physician should be informed of all medications the patient is taking. Specific interactions vary based on the specific drug.
warnings and precautionsPatients with a history of significant or uncontrolled lung disease should be monitored closely. Patients should be cautioned to rinse their mouths after inhalation to prevent oral candidiasis. Use with caution in patients with impaired liver or kidney function.
2
drug classLong-Acting Beta2 Agonists (LABAs)
general information
classificationBronchodilators, Long-Acting Beta-Agonists
pharmacokineticsSystemic absorption occurs, but less so when inhaled. Mechanism of action involves stimulating beta2 receptors in the lungs. Metabolism and excretion vary based on the specific drug.
additional informationsImportant to note that the LABA alone is not an appropriate treatment for acute asthma attacks. Consult your physician for appropriate treatment.
specific medications
1
nameSalmeterol
dosage and administrationSpecific dosage varies by patient. Consult your physician.
indicationsBronchodilation in patients with asthma or chronic obstructive pulmonary disease (COPD). Often used with inhaled corticosteroids for combination therapy.
side effects
1Tremor
2Anxiety
3Palpitations
4Headache
5Cardiac problems in susceptible individuals
contraindicationsHypersensitivity to the drug or components; some cardiac conditions; severe uncontrolled hypertension.
interactionsPossible interactions with other medications; consult your physician.
warnings and precautionsDo not use for acute bronchospasm. Use caution in patients with cardiovascular conditions. This is not a rescue inhaler.

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