| name | Kyleena |
| classification | Levonorgestrel-releasing intrauterine system (IUS) |
| pharmacokinetics | Kyleena releases levonorgestrel locally within the uterus. The drug is absorbed systemically at very low levels compared to oral contraceptives. Levonorgestrel's primary mechanism of action is to thicken cervical mucus, making it difficult for sperm to reach the egg. It also affects the uterine lining, making it less receptive to implantation. The exact pharmacokinetic profile varies significantly based on individual factors and should not be used as a primary determinant for treatment. |
| suggested dosage | Kyleena is a single-use device that is implanted in the uterus and doesn't require daily dosage. |
| indications | | 1 | Contraception | | 2 | Management of menorrhagia (heavy menstrual bleeding) |
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| safety in pregnancy | Kyleena is absolutely contraindicated during pregnancy. Removal of the device should be considered as soon as pregnancy is confirmed. |
| safety in breastfeeding | Kyleena is generally considered safe for use during breastfeeding, but there might be a small reduction in milk production. Consult your doctor for specific advice. |
| side effects | | 1 | Irregular bleeding (spotting, breakthrough bleeding, amenorrhea) | | 2 | Cramps or pain in the lower abdomen | | 3 | Headache | | 4 | Mood changes | | 5 | Breast tenderness | | 6 | Nausea | | 7 | Weight fluctuations | | 8 | Pelvic pain | | 9 | Infection (rare) |
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| alternatives | |
| contraindications | | 1 | Known or suspected pregnancy | | 2 | Unexplained vaginal bleeding | | 3 | Pelvic inflammatory disease (PID) | | 4 | Uterine fibroids | | 5 | Suspected or known uterine abnormalities | | 6 | Active pelvic infection | | 7 | Known hypersensitivity to levonorgestrel |
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| interactions | Limited drug interactions are expected. However, individual responses may vary. Consult your doctor about any medications you are taking. |
| warnings and precautions | | 1 | Regular check-ups with your doctor are crucial. | | 2 | Early removal may be necessary if pregnancy is suspected. | | 3 | Prompt medical attention is required for severe or unusual side effects. | | 4 | May delay the diagnosis of certain gynecological conditions if any pre-existing conditions exist. | | 5 | The IUS is not a replacement for STD precautions. |
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| additional informations | | 1 | Kyleena is inserted by a healthcare professional. | | 2 | Kyleena is a long-acting reversible contraceptive (LARC) method. | | 3 | Expected duration of use is 5 years. | | 4 | The device can be removed earlier if desired. | | 5 | Individual responses to Kyleena can vary. |
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| patient details | |
