| name | Methyl Salicylate |
| Classification | Topical Analgesic/Anti-inflammatory |
| Pharmacokinetics | Methyl salicylate is a topical analgesic and anti-inflammatory agent. It is readily absorbed through the skin and metabolised primarily in the liver. Systemic absorption is typically low, but may be increased with significant skin surface application or impaired skin integrity. Excretion primarily occurs through the kidneys. |
| suggested dosage | Dosage is highly dependent on the specific formulation and intended use (e.g., muscle rub, liniment). Always follow product-specific instructions carefully. A general guideline is to apply a thin layer to the affected area as needed, typically 2-4 times per day. Do not exceed the recommended amount. |
| indications | Topical methyl salicylate is used to relieve mild to moderate pain and discomfort associated with muscle aches, sprains, strains, and other musculoskeletal conditions. It works by producing a warming sensation that may temporarily reduce pain and inflammation. |
| safety in pregnancy | Limited data exists regarding the safety of methyl salicylate use during pregnancy. While systemic absorption is generally low, caution is warranted. Consult with a healthcare provider before use during pregnancy. |
| safety in breastfeeding | Limited data regarding use during breastfeeding. Due to the potential for low-level systemic absorption, consult with a healthcare provider before using. |
| side effects | | 1 | Skin irritation, redness, or rash (common) | | 2 | Skin dryness (potential) | | 3 | Allergic reactions (uncommon) | | 4 | Mild systemic effects (e.g., headache, dizziness) – rarely seen with topical application |
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| contraindications | | 1 | Known hypersensitivity or allergy to methyl salicylate or other salicylates | | 2 | Open wounds or damaged skin at the application site | | 3 | Children under a certain age (refer to product information). | | 4 | Use on large areas of skin for extended periods of time, as this might increase systemic absorption and related side effects. | | 5 | Certain skin conditions like dermatitis, eczema. |
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| interactions | While systemic absorption is usually low, potential interactions with other medications should be considered. Inform your doctor of all medications you are currently taking, especially those that affect the liver or kidneys. |
| warnings and precautions | | 1 | Avoid contact with eyes, mucous membranes, and large open wounds. | | 2 | Apply a thin layer and avoid over application. | | 3 | Stop use if irritation develops. | | 4 | Keep out of reach of children. | | 5 | Do not use for more than 10 days without consulting a doctor, if symptoms persist or worsen. |
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| additional informations | | 1 | Methyl salicylate can be absorbed through the skin, so avoid contact with the eyes and mucous membranes. | | 2 | Use only as directed on the product label. | | 3 | If you experience any significant side effects, discontinue use and consult a doctor. |
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