| name | Prednisone |
| classification | Glucocorticoid, Corticosteroid |
| pharmacokinetics | Prednisone is an oral corticosteroid metabolized in the liver to prednisolone, the active form. Its half-life varies based on individual metabolism and is relatively short. Prednisone is primarily excreted in the urine. |
| dosage | Dosage varies greatly depending on the condition and patient. A starting dose for a 25-year-old male weighing 70 kg might be 5mg orally once daily *in a non-critical situation*, but this is only an example and should *never* be used without a healthcare professional's guidance. Precise dosage and administration are crucial and should be determined and adjusted by a qualified medical professional. |
| indications | | 1 | Rheumatoid arthritis | | 2 | Lupus erythematosus | | 3 | Asthma | | 4 | Crohn's disease | | 5 | Ulcerative colitis | | 6 | Allergic reactions | | 7 | Some types of cancer | | 8 | Severe skin conditions |
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| safety in pregnancy | Prednisone use during pregnancy requires careful consideration by a doctor. Potential risks to the fetus must be weighed against potential benefits to the mother. |
| safety in breastfeeding | Prednisone can pass into breast milk. The potential risks to the infant must be carefully evaluated against the mother's need for the medication. Consult with a doctor. |
| side effects | | 1 | Weight gain | | 2 | Fluid retention | | 3 | Increased appetite | | 4 | Mood changes | | 5 | Osteoporosis | | 6 | Hyperglycemia | | 7 | Cushing's syndrome (with prolonged use) | | 8 | Peptic ulcers | | 9 | Muscle weakness | | 10 | Thinning skin | | 11 | Easy bruising | | 12 | Increased risk of infections | | 13 | Sleep disturbances |
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| alternatives | |
| contraindications | | 1 | Hypersensitivity to corticosteroids | | 2 | Active untreated infection | | 3 | Glaucoma | | 4 | Severe peptic ulcer disease | | 5 | Myasthenia gravis |
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| interactions | Prednisone can interact with numerous medications, including NSAIDs, certain antibiotics, and immunosuppressants. Always inform your doctor of all medications you are taking. |
| warnings and precautions | Patients with a history of diabetes, high blood pressure, or osteoporosis should be monitored closely. Gradual tapering of the dose is crucial when stopping prednisone to avoid adrenal insufficiency. |
| additional informations | Always follow your doctor's prescribed dosage and duration. Do not adjust or discontinue the medication without consulting your doctor first. Prednisone should only be used if the benefits outweigh the risks. Consult with a healthcare professional for a personalized treatment plan. |
| patient details | | example age | 25 | | example weight | 70 |
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