name | Hydrocortisone Ointment |
classification | Corticosteroid Topical |
pharmacokinetics | Hydrocortisone is a potent corticosteroid. Following topical application, it is absorbed transdermally and exerts its effects locally. Absorption into the systemic circulation is generally minimal with properly used ointments. However, with prolonged use or application to large areas, systemic effects can occur. Metabolism occurs primarily in the liver, with excretion primarily in the urine. |
suggested dosage | Apply a thin layer of ointment to the affected area 1-3 times daily as directed by a physician. Avoid applying the ointment over large areas, or for extended periods of time without consulting a doctor. |
indications | Treatment of inflammatory skin conditions such as eczema, contact dermatitis, psoriasis, and insect bites. |
safety in pregnancy | Generally considered safe for use during pregnancy. Use during pregnancy and lactation should only be under the direct supervision of a physician, and if other options aren't viable. |
safety in breastfeeding | Limited data on breast milk concentrations. Use cautiously, especially during long-term use, and if high amounts are being applied. Consult your doctor if used during breastfeeding. |
side effects | 1 | Skin irritation (e.g., redness, itching, burning, dryness) | 2 | Skin thinning | 3 | Striae (stretch marks) | 4 | Local skin atrophy | 5 | Acneiform eruptions | 6 | Candidiasis |
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alternatives | |
contraindications | 1 | Known hypersensitivity to hydrocortisone or any other ingredients in the formulation | 2 | Ocular use | 3 | Use over large areas for long periods without a physician's supervision. |
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interactions | Limited significant interactions exist with topical use in a healthy individual. However, concomitant use of other topical medications should be discussed with a physician to avoid unwanted effects. |
warnings and precautions | Avoid contact with the eyes. Discontinue use and consult a physician if signs of infection or worsening of the condition occur. Do not use on open wounds unless directed by a doctor. |
additional information | Ointments tend to have higher potency than creams. The specific formulation of hydrocortisone ointment will influence the suggested dosage, thus adherence to physician's recommendations is essential. |