| name | Prednisolone Cream |
| Classification | Corticosteroid Topical |
| Pharmacokinetics | Prednisolone, a synthetic glucocorticoid, is applied topically. The drug is readily absorbed through the skin, though the systemic absorption is generally low. The extent of absorption depends on the concentration, area of application, and duration of use. Limited data is available on specific pharmacokinetic parameters in humans after topical application. |
| suggested dosage | Dosage depends on the specific condition being treated. Consult a physician for appropriate recommendations. Commonly, a thin film of cream is applied to the affected area once or twice daily. The frequency should not exceed twice daily to minimize systemic absorption and potential side effects. |
| indications | Prednisolone cream is primarily used to treat inflammatory skin conditions such as eczema, dermatitis, and other localized skin rashes and conditions characterized by inflammation. |
| Safety in pregnancy | Limited data is available. Use only as prescribed by a physician and under careful consideration of potential risks to the fetus. Avoid prolonged use or high-dosage applications during pregnancy, unless benefits outweigh risks. |
| Safety in breastfeeding | Limited data is available. Discuss potential risks and benefits with a healthcare provider before use during breastfeeding. Avoid prolonged use or high-dosage applications during breastfeeding, unless benefits outweigh risks. |
| side effects | | 1 | Skin irritation, redness, itching, burning, or dryness. | | 2 | Thinning of the skin (atrophy) | | 3 | Skin discoloration or bruising. | | 4 | Eczema | | 5 | Infection at the application site | | 6 | Systemic side effects are uncommon with topical application but may include Cushing's syndrome-like symptoms with prolonged use. | | 7 | Facial flushing |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to prednisolone or any of its components. | | 2 | Active skin infections or conditions that would not be appropriately treated with topical steroids. | | 3 | Open wounds or skin lesions over the application area. |
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| interactions | Prednisolone cream may interact with other topical medications, or systemic medications that affect the skin or inflammation. Consult with a physician about concomitant use of other medications. |
| warnings and precautions | | 1 | Avoid contact with eyes. | | 2 | Do not apply to large areas of the body. | | 3 | Do not use for prolonged periods without consulting a physician. | | 4 | Monitor for signs of systemic effects, such as weight gain, mood changes, or increased appetite. | | 5 | Monitor the patient for any signs of infection or worsening of the condition. | | 6 | Do not use on damaged or broken skin. | | 7 | Do not use if pregnant or breast-feeding without proper consultation from a physician. |
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| additional information | Always follow the prescribed dosage and application instructions. The cream should be applied thinly and gently massaged into the affected area. Always clean and dry the skin before application. Report any unusual symptoms or side effects to the prescribing physician immediately. |
| patient specific details | | age | 25 | | weight | 70 kg | | notes | This information is for general knowledge only, and does not constitute medical advice. Always seek the advice of a medical professional for any health concerns. |
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