| name | Ulipristal Acetate |
| classification | Selective progesterone receptor modulator (SPRM) |
| pharmacokinetics | | absorption | Rapidly absorbed after oral administration, reaching peak plasma concentrations within 1-2 hours. | | distribution | Distributed throughout the body, with high concentrations in the liver. | | metabolism | Primarily metabolized by the liver, with some contribution from the kidneys. Follows first-pass effect. | | excretion | Excreted primarily in the bile and faeces. |
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| suggested dosage | | emergency contraception | A single dose of 30 mg taken as soon as possible, but within 120 hours (5 days) after unprotected sex. Do not take more than one dose within 24 hours. | | other uses | Ulipristal acetate is not typically prescribed for routine use, and dosages will vary depending on the specific indication. |
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| indications | | 1 | Emergency contraception (within 120 hours after unprotected sex) | | 2 | Treatment of uterine fibroids (in certain cases, with more research needed) |
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| safety in pregnancy | | category x | Pregnancy Category X. Ulipristal acetate is contraindicated during pregnancy. | | details | Animal studies have shown adverse effects on the developing fetus and there are no adequate and well-controlled studies in pregnant women. Ulipristal acetate should not be used during pregnancy. |
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| safety in breastfeeding | | details | Limited data available. It is unknown if ulipristal acetate is present in breast milk. Discontinuation of breastfeeding is advised. | | recommendation | Use with caution and consider the potential benefits and risks. |
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| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Abdominal pain | | 4 | Headache | | 5 | Fatigue | | 6 | Dizziness | | 7 | Breast tenderness | | 8 | Bleeding irregularities (especially in initial treatment) | | 9 | Rarely, more serious adverse effects such as hypersensitivity reactions. |
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| alternatives | |
| contraindications | | 1 | Pregnancy | | 2 | Known hypersensitivity to ulipristal acetate or any of its components. | | 3 | Severe liver disease |
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| interactions | | 1 | Certain medications that affect liver enzymes, possibly leading to increased or decreased ulipristal acetate levels. | | 2 | May interact with some hormonal medications, and certain medications for other conditions. Consult doctor before taking other medications. |
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| warnings and precautions | | 1 | Not recommended for routine birth control. | | 2 | Consult a physician for proper dosage and monitoring. | | 3 | Not a substitute for regular contraception in preventing unintended pregnancies. | | 4 | May affect menstrual cycle for a short period. | | 5 | Patient should be carefully monitored for any adverse effects. |
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| additional informations | | 1 | Effective when used promptly after unprotected sex. The sooner it is taken, the more effective it is. | | 2 | For emergency contraception use only, when other methods are not possible. | | 3 | Consult with a healthcare professional for personalized medical advice and to discuss any concerns. |
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| patient details | |
| important note | Ulipristal acetate is primarily used in women. While the provided information is factual, it is crucial to consult with a healthcare professional for appropriate medical advice, especially for male patients. |
