| name | Calcipotriol |
| Classification | Vitamin D Analog, Topical Calcipotriene |
| Pharmacokinetics | Calcipotriol is a vitamin D analog that is primarily absorbed topically. It is converted to its active metabolite within the skin. Systemic absorption is minimal, but it can still affect calcium and phosphorus levels. Its bioavailability is low. |
| suggested dosage | Dosage varies depending on the specific condition and product form. Consult with a healthcare professional for the proper dosage and application method. General guidance on application will be given by the doctor but it is very important to strictly follow the instructions provided by the healthcare professional for best results. |
| indications | Calcipotriol is primarily used to treat psoriasis, specifically plaque psoriasis. It works by reducing inflammation and cell growth in the affected skin areas. |
| Safety in pregnancy | Limited data is available on the safety of calcipotriol during pregnancy. However, it is generally considered to be a topical treatment, so risk to the fetus is relatively low. Pregnant women should consult with their doctor before using calcipotriol. |
| Safety in breastfeeding | Limited data is available on the safety of calcipotriol in breastfeeding women. Because of the minimal systemic absorption, risk to the infant is low but consulting a healthcare professional before using this drug is advised. |
| side effects | | 1 | Skin irritation (e.g., redness, burning, itching, dryness) | | 2 | Local skin reactions (e.g., rash, scaling) | | 3 | Systemic effects (e.g., hypercalcemia, increased blood calcium levels), if significantly absorbed systemically, which is rare. | | 4 | Mild flu-like symptoms | | 5 | Interference with other topical treatments | | 6 | Potential skin reactions if used on open wounds or inflamed skin. |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to calcipotriol or other vitamin D analogs | | 2 | Severe skin infections or conditions that might be worsened by the topical treatment |
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| interactions | Calcipotriol may interact with other medications that affect calcium and vitamin D metabolism. It is important to inform your doctor of all medications you are taking. |
| warnings and precautions | | 1 | Apply the cream thinly, evenly, and sparingly to the affected skin areas as prescribed by the doctor. | | 2 | Avoid contact with the eyes, and use caution when applying to areas near the eyes. | | 3 | Monitor for any signs of increased irritation or adverse reactions. | | 4 | Do not apply to open wounds or broken skin. | | 5 | Inform your doctor about any other health conditions you may have. | | 6 | Adherence to the recommended dosage and application frequency is vital. | | 7 | Avoid prolonged sun exposure, when using this medication. | | 8 | Potential for hypercalcemia is possible, especially with prolonged or excessive topical usage. This requires monitoring of blood calcium levels by the physician. | | 9 | Do not use this drug in combination with other topical drugs without explicit doctor instructions. | | 10 | In severe cases of psoriasis, additional therapies may need to be used. |
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| additional information | Calcipotriol is a topical therapy for plaque psoriasis and should not be used to treat other skin conditions without doctor guidance. This information is for general knowledge only and should not be considered a substitute for professional medical advice. Always consult with your physician regarding appropriate diagnosis, treatment plan, and any concerns related to your health or medication use. |
