| name | Beclomethasone |
| classification | Corticosteroid, inhaled |
| pharmacokinetics | Beclomethasone dipropionate is a potent corticosteroid delivered via inhalation. Following inhalation, it is primarily absorbed by the lungs, with minimal systemic absorption. The extent of systemic absorption depends on the dose, frequency, and patient factors (e.g., lung function). Most of the drug is metabolized in the liver. Excretion primarily occurs through the kidneys, although some metabolites may be excreted via the bile. |
| suggested dosage | Dosage varies significantly based on the specific indication and patient response. A 25-year-old male weighing 70 kg would typically start with a low dose and titrate as needed. It's crucial to consult a physician for appropriate dosage and duration of treatment. Specific doses should never be taken without explicit medical advice, as improper dosage can lead to negative consequences. |
| indications | Beclomethasone is primarily used for the long-term treatment of asthma and other chronic inflammatory lung diseases, including chronic obstructive pulmonary disease (COPD) and allergic rhinitis. It is also used for conditions requiring topical corticosteroid treatment, like skin conditions. Use is usually indicated when other treatments prove insufficient or less effective. |
| safety in pregnancy | Beclomethasone use in pregnancy is generally considered safe when taken as prescribed for asthma or respiratory conditions. However, inhaled corticosteroids may cross the placental barrier, and there's a potential risk of developmental issues. The decision to use this medication during pregnancy should be made cautiously by a physician. Careful monitoring is recommended. |
| safety in breastfeeding | Beclomethasone is likely to be present in breast milk. The levels are generally considered low and unlikely to cause significant harm to the infant. The use of beclomethasone in breastfeeding women is acceptable if needed, but a physician should be consulted to discuss possible risks and benefits. |
| side effects | | 1 | Oropharyngeal candidiasis (thrush) | | 2 | Hoarseness | | 3 | Cough | | 4 | Headache | | 5 | Tremors | | 6 | Insomnia | | 7 | Increased appetite | | 8 | Facial flushing | | 9 | Back pain | | 10 | Weight gain | | 11 | Adrenal insufficiency (rare, if systemic absorption is high) | | 12 | Growth suppression (potential in children and adolescents) |
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| alternatives | |
| contraindications | Hypersensitivity to beclomethasone or other corticosteroids. Use with caution in patients with systemic fungal infections, or severe infections. Patients with severe underlying cardiac, renal or hepatic dysfunction should also be closely monitored |
| interactions | Concurrent use of other corticosteroids (oral or topical), or immunosuppressants may increase the risk of side effects or reduce the effectiveness of therapy. It's important to inform your physician about all medications and supplements being taken. |
| warnings and precautions | | 1 | Potential for increased blood sugar levels | | 2 | Avoid inhalation into the eyes. If inhaled into the eyes, immediately flush with copious amounts of water. | | 3 | Report any signs of infection in the mouth or throat | | 4 | Avoid smoking during treatment | | 5 | Do not abruptly stop taking the medication if prescribed for long-term use. The dose should be gradually decreased by your physician to avoid adrenal insufficiency | | 6 | Patients with history of diabetes or hypertension may require increased monitoring | | 7 | Proper technique for inhalation is critical to minimize systemic side effects. |
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| additional information | Beclomethasone is typically delivered as a metered-dose inhaler (MDI). Proper use of the MDI is essential to maximize therapeutic benefits and minimize unwanted side effects. Patients must be educated on the correct inhalation technique. Long-term use necessitates monitoring for potential side effects and adjustment of the regimen as necessary. Consult your physician for specific instructions. |
| patient specific considerations | | age | 25 (no specific issues expected related to age) | | weight | 70 kg (no specific issues expected related to weight) |
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