| name | Betamethasone Dipropionate Ointment |
| classification | Corticosteroid Topical |
| pharmacokinetics | Betamethasone dipropionate is a topically applied corticosteroid. Its absorption through the skin is limited, primarily in areas with damaged skin or excessive inflammation. The drug is not systemically absorbed to a significant degree, minimizing systemic side effects. However, absorption can occur with significant inflammation or large application areas. The ointment form allows for slow, continuous delivery of the medication to the affected area. |
| suggested dosage | Dosage is dependent on the severity and location of the skin condition. Consult a physician for appropriate dosage. Commonly, a thin layer of ointment is applied to the affected area 1-2 times daily, or as prescribed by a healthcare professional. Avoid using excessive amounts or frequent applications to reduce risk of skin irritation or thinning. Do not apply over large open wounds or irritated areas where the skin is broken, as this may increase absorption. |
| indications | Betamethasone dipropionate ointment is indicated for the topical treatment of inflammatory dermatological conditions, such as: atopic dermatitis, contact dermatitis, eczema, lichen planus, psoriasis, and other inflammatory skin conditions, where topical corticosteroid therapy is indicated. |
| safety in pregnancy | Betamethasone dipropionate is generally considered safe for use during pregnancy, but only under the direct supervision of a physician. Use should be limited to areas of minimal contact with the fetus and only where the potential benefit outweighs any potential risk. No substantial human data directly assesses risks and benefits in this population. Consult a doctor. Do not self-treat. |
| safety in breastfeeding | Limited data is available regarding the safety of betamethasone dipropionate during breastfeeding. Use is not typically recommended unless the potential benefit to the mother outweighs the potential risk to the infant. Consult a physician, particularly if the condition affects the area of the breast. |
| side effects | | 1 | Skin irritation (e.g., redness, itching, burning, dryness) | | 2 | Skin atrophy (thinning of the skin, especially with prolonged use) | | 3 | Striae (stretch marks) | | 4 | Acneiform eruptions | | 5 | Hirsutism (excessive hair growth) | | 6 | Telangiectasia (dilated blood vessels) | | 7 | Perioral dermatitis (redness and inflammation around the mouth) | | 8 | Delayed wound healing |
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| alternatives | |
| contraindications | Known hypersensitivity to betamethasone or any of the ointment's components, active skin infections or fungal infections of the affected area, or use over large areas of skin. |
| interactions | Simultaneous use with other topical medications may potentially affect absorption or efficacy. Consult a physician if using other topical or systemic medications. Increased absorption may occur with concurrent use of other topical corticosteroid medications. |
| warnings and precautions | | 1 | Avoid prolonged use or application to large areas of skin, as this may increase the risk of systemic side effects. | | 2 | Do not use on damaged or broken skin. | | 3 | Monitor the treated area for any signs of infection or worsening of the condition. | | 4 | Do not use on the face or other areas where prolonged or extensive use is not recommended without appropriate professional consultation. | | 5 | Monitor patients for signs of adrenal insufficiency if used for an extended period. |
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| additional information | Patient age and weight are generally not factors in the dosing of topical medications in this class. Individual needs are assessed by the prescribing physician. |
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