name | Clobetasol Propionate Topical |
classification | Corticosteroid, Topical |
pharmacokinetics | Clobetasol propionate is a potent corticosteroid that is readily absorbed through the skin. The exact pharmacokinetic profile in humans is not fully defined in detail; however, it is considered rapidly metabolized and eliminated in the liver. Topical application does not result in systemic circulation to a significant degree. |
suggested dosage | The information provided here is for general knowledge and informational purposes only, and does not constitute medical advice. Always consult with a healthcare professional for personalized advice. Dosage and frequency of topical application for clobetasol propionate will vary based on the severity and location of the skin condition being treated. Your doctor will prescribe the appropriate regimen. |
indications | Clobetasol propionate topical is used to treat a variety of inflammatory skin conditions, including: psoriasis, eczema, allergic dermatitis, contact dermatitis, and other inflammatory dermatoses characterized by redness, inflammation, and scaling or blistering. It is indicated for short-term use only to reduce symptoms and inflammation. Chronic use should be avoided. |
safety in pregnancy | Clobetasol propionate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Limited data exists about long-term effects, therefore, use during pregnancy should only be done under direct medical supervision. Consult with your healthcare provider for personalized advice. |
safety in breastfeeding | Clobetasol propionate is not recommended for use on areas of skin that could come into contact with the infant during breastfeeding. The potential for systemic absorption and its effects on a breastfeeding infant are poorly understood. If use is absolutely necessary, it is essential to discuss with a healthcare provider who will monitor and discuss specific risks for the infant. |
side effects | Common side effects include skin thinning (atrophy), striae (stretch marks), hypopigmentation (loss of skin color), and skin irritation. In rare cases, systemic effects can occur if used on extensive skin areas or if the skin is compromised. More serious side effects are possible, but less common. It is important to report any unusual symptoms to your doctor. |
alternatives | |
contraindications | Clobetasol propionate topical is contraindicated in patients with a history of hypersensitivity (allergy) to clobetasol or any component of the formulation. |
interactions | No significant drug-drug interactions are reported with clobetasol propionate when used topically. However, it is important to inform your doctor about all medications you are currently taking to avoid any potential interaction or adverse effect. |
warnings and precautions | Avoid using clobetasol propionate on the face, groin, or underarm areas unless prescribed by a doctor due to the risk of severe side effects. Avoid prolonged use, even when prescribed, as topical steroids can lead to skin thinning and atrophy. Always follow the prescribed dosage instructions and do not increase or decrease dosage without consulting a healthcare provider. If symptoms worsen or persist, seek medical attention. |
additional informations | Clobetasol propionate is a potent corticosteroid, and topical use should be closely monitored by a healthcare professional. The patient's age and weight are not critical factors in determining the dosage for topical corticosteroids, but the severity of the skin condition being treated will guide the prescription. Follow your physician's instructions carefully. It is critical to use only the prescribed amount for the designated time period as directed. |
patient specific considerations | Age (25) and weight (70 kg) are not a factor in this topical medication's dosage. |