| name | Fluticasone Propionate Topical |
| Classification | Corticosteroid, Topical |
| Pharmacokinetics | Fluticasone propionate is a potent corticosteroid that is applied topically. It is readily absorbed through the skin, though systemic absorption is generally low, especially with proper application techniques. The drug's effects are primarily localized at the site of application. Metabolism is primarily hepatic and excretion is primarily via the renal route. |
| suggested dosage | Dosage is highly dependent on the specific condition being treated and the formulation. It's crucial to follow the instructions provided by the prescribing physician and any accompanying product information. Generally, topical application is advised with a thin film applied as needed, usually 1-2 times daily. The frequency and amount should never exceed the prescribed dosage or frequency. |
| indications | Fluticasone propionate topical is used to treat inflammatory and allergic skin conditions, such as localized dermatitis, eczema, and psoriasis, when systemic treatment is inappropriate or undesirable. It may also be utilized for conditions like allergic contact dermatitis, and certain types of skin rashes. |
| Safety in pregnancy | Limited human data is available. While topical corticosteroids are generally considered relatively safe in pregnancy, consult your doctor, especially during the first trimester. It's crucial to discuss the potential risks and benefits for each individual case. Topical corticosteroids do not typically result in systemic effects, however, if absorption is significant there may be consequences. It is best to avoid use during pregnancy unless the benefits outweigh the risks. |
| Safety in breastfeeding | Limited human data is available regarding the safety of fluticasone propionate topical for use in breastfeeding mothers. It is important to discuss potential risks with a healthcare professional. Again, while topical absorption is generally low, you must weigh risks and benefits, and discuss any potential impacts with your physician. |
| side effects | | 1 | Skin irritation (e.g., redness, burning, itching, dryness) | | 2 | Skin thinning (atrophy) | | 3 | Striae (stretch marks) | | 4 | Skin infection at the application site | | 5 | Systemic effects (rare but possible), especially if used over large surface areas or if the patient has a history of skin conditions. | | 6 | Possible worsening of pre-existing skin conditions. |
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| alternatives | |
| contraindications | Hypersensitivity to fluticasone propionate or other corticosteroids. Use with caution, if at all, in patients with active or suspected skin infections, or conditions with impaired wound healing. |
| interactions | No significant interactions are anticipated with commonly used medications. However, it is important to inform your doctor of all medications and supplements you are currently taking. The use of other topical medications in combination may affect the efficacy or safety profile. |
| warnings and precautions | | 1 | Do not use on broken or infected skin. | | 2 | Avoid contact with eyes. | | 3 | Use only as directed. | | 4 | Discontinue use and consult a doctor if irritation or worsening of skin condition occurs. | | 5 | Monitor for systemic effects if applied to large areas or in prolonged use. |
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| additional information | Age and weight are generally not critical factors in determining topical corticosteroid dosage for a healthy adult. Application should be on a small area as needed. |
| patient specific details | | age | 25 | | weight | 70 | | other conditions | None specified |
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