name | Crotamiton |
classification | Antiparasitic, Topical |
pharmacokinetics | Crotamiton is a topical agent. The exact absorption is variable and depends on the formulation and extent of skin contact. Minimal systemic absorption occurs, and the primary effects are local. Metabolism primarily occurs in the liver, with excretion predominantly through the kidneys. However, there's no definitive pharmacokinetic data specifically for a 25-year-old male weighing 70kg. Data is often extrapolated from larger studies. |
suggested dosage | Dosage is typically determined by the extent and severity of the condition. Follow the instructions on the prescription or product label. Topical application is usually twice a day for a period of weeks, depending on the response. |
indications | Topical crotamiton is primarily used to treat scabies (itch mite infestation). It can also be used in the treatment of some types of fungal infections, such as ringworm. |
safety in pregnancy | Limited data exist regarding the safety of crotamiton use during pregnancy. Consult with your healthcare provider. Use should be avoided during first trimester if possible. Use is considered possibly safe during second and third trimester under medical supervision if benefit outweighs risk. |
safety in breastfeeding | Limited data regarding safety in breastfeeding mothers. Avoid use during breastfeeding if possible. Consult a healthcare provider if needed. |
side effects | 1 | Skin irritation (e.g., redness, itching, burning) | 2 | Skin rash | 3 | Allergic reactions (rare) | 4 | Contact dermatitis (in some cases) |
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alternatives | |
contraindications | 1 | Known hypersensitivity or allergy to crotamiton or other ingredients in the formulation | 2 | Open or broken skin lesions in the area of application | 3 | Use over extensive areas of skin (consider potential for systemic side effects). | 4 | Severe hepatic impairment |
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interactions | Limited drug interactions. Avoid concurrent use of other topical skin irritants. Consult your doctor if taking other medications, including herbal remedies. |
warnings and precautions | 1 | Apply only to affected areas. | 2 | Avoid contact with eyes, mucous membranes, and open wounds. | 3 | If irritation develops, discontinue use and contact a healthcare professional. | 4 | Do not use on large body areas without appropriate guidance. | 5 | Follow the recommended duration of therapy. | 6 | Keep out of reach of children. |
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additional information | Crotamiton is generally a safe and effective treatment. However, its use requires careful monitoring and consideration of potential side effects, especially in individuals with pre-existing skin conditions. |
patient specific details | age | 25 | weight | 70 kg | important notes | This information is for educational purposes only and is not a substitute for professional medical advice. Always consult with a qualified healthcare provider before starting any new medication or treatment regimen. |
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