| name | Fluocinolone Acetonide Topical Cream |
| Classification | Corticosteroid Topical |
| Pharmacokinetics | Fluocinolone acetonide is a potent corticosteroid that acts locally by suppressing inflammation. It is not systemically absorbed to a significant extent in healthy individuals, but absorption can increase with the presence of skin lesions or increased application. The drug remains in the skin, and there is no accumulation. |
| suggested dosage | | adult | Apply a thin layer of cream to the affected area 1-2 times daily. Avoid application on large areas of skin or for extended periods of time without consulting a physician. Follow physician instructions for dosage specific to the condition. |
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| indications | | 1 | Treatment of inflammatory skin conditions such as eczema, contact dermatitis, and psoriasis. Specifically indicated for localized, inflammatory dermatologic conditions requiring potent topical corticosteroid therapy. | | 2 | Use only under a physician's direction. |
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| Safety in pregnancy | Limited data are available on the use of topical corticosteroids like Fluocinolone Acetonide during pregnancy. Although systemic absorption is generally low, potential risks to the fetus are unknown and should be discussed with the treating physician. |
| Safety in breastfeeding | Use with caution. Although systemic absorption is generally low, the potential for systemic effects and/or transfer into breast milk requires close monitoring and consideration by the prescribing physician. Avoid topical applications near the breast. |
| side effects | | 1 | Skin thinning (atrophy) | | 2 | Striae (stretch marks) | | 3 | Telangiectasia (small dilated blood vessels) | | 4 | Acneiform eruptions | | 5 | Purpura | | 6 | Skin infections (secondary bacterial, fungal, or viral) | | 7 | Hypertrichosis (excessive hair growth) | | 8 | Burning, itching or stinging at the application site | | 9 | Hypopigmentation (temporary or permanent loss of skin color) | | 10 | Systemic effects if used in large quantities over a prolonged period (rare but possible) |
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| alternatives | |
| contraindications | | 1 | Active skin infections in the area of application | | 2 | Known hypersensitivity to fluocinolone acetonide or other corticosteroids | | 3 | Ocular use (use in or near the eye). |
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| interactions | | 1 | No significant interactions are expected with oral medications. However, concomitant use with other topical medications, such as calcineurin inhibitors, may require special consideration. Consult with physician for further details. |
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| warnings and precautions | | 1 | Do not use on damaged, broken, or infected skin. | | 2 | Use the lowest effective dose for the shortest duration of time necessary to control the condition. | | 3 | Avoid prolonged use in children, or on large areas of skin without consulting a physician. | | 4 | Monitor for signs of systemic corticosteroid effects, such as increased appetite, mood changes, or weight gain, especially with prolonged or extensive use. | | 5 | Do not use on the face without consulting a physician due to the possibility of adverse reactions. |
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| additional informations | | 1 | Proper skin hygiene is crucial, and consult a physician for any concerns or unusual symptoms. Apply as directed by a licensed healthcare professional. |
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| patient specific notes | | age | 25 years | | weight | 70 kg | | potential impact | The patient's age and weight are not expected to significantly alter the overall drug response, but must be considered with the dosage. |
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