| name | Hydrocortisone Cream 1% |
| classification | Topical corticosteroids |
| pharmacokinetics | Hydrocortisone is a potent corticosteroid that is readily absorbed through the skin. The cream formulation is designed for topical use, limiting systemic absorption. Peak concentrations at the application site are achieved within a few hours and may persist for up to a day depending on concentration and extent of application. Metabolism primarily occurs in the liver, and excretion is mainly via the kidneys. |
| suggested dosage | Apply a thin layer of cream to the affected area 1-4 times daily, as directed by a healthcare professional. The frequency and duration of treatment should be based on the severity and location of the skin condition. |
| indications | Hydrocortisone cream 1% is indicated for the treatment of mild to moderate inflammatory skin conditions such as: eczema, dermatitis, pruritus, insect bites, and minor skin irritations. |
| safety in pregnancy | Hydrocortisone is generally considered safe for use during pregnancy in topical applications at appropriate dosage. However, there are theoretical concerns regarding the potential for systemic effects. Use during pregnancy should be carefully considered in consultation with a healthcare professional, and dosage should be limited to the minimum effective amount. |
| safety in breastfeeding | Limited data exists on hydrocortisone's effects in breastfeeding women when used topically. It is believed that systemic absorption is minimal, and the cream may be applied to skin areas not in direct contact with the baby. However, it is still recommended that women consult with their doctor before using topical corticosteroid preparations during breastfeeding. |
| side effects | Common side effects (often transient and mild) include skin irritation, redness, burning, itching, or dryness at the application site. Rarely, more serious systemic effects (e.g., Cushing's syndrome) may occur from high dosage or prolonged use of potent topical corticosteroids. Individual reactions may vary. |
| alternatives | |
| contraindications | Patients with known hypersensitivity to hydrocortisone or any of the inactive ingredients should not use this product. Avoid use in areas with open wounds or lesions, as the skin may not be as protective against absorption. |
| interactions | Concurrent use with other topical medications or systemic medications (including immunosuppressants) may impact absorption or result in unexpected effects. Consult a healthcare professional if using other topical or systemic medications. |
| warnings and precautions | Do not use on large areas of skin, or for extended periods of time without consulting a healthcare provider. If irritation or other side effects occur, discontinue use and consult a doctor. For children, use only as directed by a physician, as the appropriate dosage and duration of use may vary. |
| additional information | Always follow the directions on the product label and instructions given by your doctor. This information is not intended as a substitute for professional medical advice. |
| patient details | |
