| name | Hydrocortisone Cream 0.5% |
| classification | Topical Glucocorticoid |
| pharmacokinetics | | absorption | Topical application results in variable absorption, dependent on skin thickness, disease activity, and extent of application. Significant systemic absorption is uncommon with properly applied, low-concentration topical preparations like this. | | metabolism | Primarily metabolized in the liver. | | excretion | Excreted primarily in the urine. |
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| suggested dosage | | adults | Apply a thin film of cream to affected area 1-4 times daily. | | notes | Avoid application to large surface areas or prolonged use unless directed by a healthcare professional. Follow the advice provided by your doctor. |
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| indications | | 1 | Treatment of mild, uncomplicated inflammatory skin conditions such as contact dermatitis, eczema, and mild forms of psoriasis (when used on small areas). | | 2 | Minor skin rashes and irritations. | | 3 | Pruritus (itching) |
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| safety in pregnancy | | summary | Use during pregnancy only if the potential benefit outweighs the potential risk. Limited data on use during pregnancy, so consult your doctor. | | additional notes | Avoid extensive use during pregnancy or during breastfeeding. |
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| safety in breastfeeding | | summary | Use during breastfeeding is possible. Limited data, so consult a healthcare professional to determine if use is appropriate. | | additional notes | Apply to affected skin areas only, avoiding contact with the nipple or breast tissue. |
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| side effects | | 1 | Local skin reactions (e.g., skin thinning, striae (stretch marks), skin atrophy, hypopigmentation (loss of skin color), folliculitis (inflammation of hair follicles)), | | 2 | Infections (due to impaired immune response), | | 3 | Systemic effects (e.g. Cushing's syndrome) are extremely unlikely with topical use if properly applied. |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to hydrocortisone or other topical corticosteroids. | | 2 | Severe skin infections (requires treatment with appropriate medication). | | 3 | Use on infected or broken skin (except as specifically directed by a healthcare provider). |
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| interactions | | 1 | Potentially additive effects with other topical corticosteroids or immunosuppressant medications | | 2 | May interact with other medications, so inform your doctor about all medications you are currently using. |
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| warnings and precautions | | 1 | Do not apply to the eyes. | | 2 | Use only as directed by a healthcare provider. | | 3 | Monitor for signs of infection or worsening skin conditions. | | 4 | Avoid prolonged use or use over large areas. | | 5 | Do not use in children without specific medical advice. |
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| additional information | | 1 | Hydrocortisone cream 0.5% is a potent topical corticosteroid. | | 2 | This information is not a substitute for professional medical advice. Always consult your physician or other qualified health care provider with any questions you may have regarding a medical condition. | | 3 | The information provided here is for educational purposes only. |
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| patient specific notes | For a 25-year-old male weighing 70 kg, the normal suggested dosage and application method remain the same as for adults. However, the patient should follow the specific instructions of their healthcare professional to avoid potential side effects. |
