| drug | Ketoconazole Shampoo |
| name | Ketoconazole Shampoo |
| classification | Antifungal, Anti-dandruff |
| pharmacokinetics | Ketoconazole is primarily absorbed through the scalp. The exact extent of systemic absorption is variable and depends on the concentration of ketoconazole in the shampoo, the duration of treatment, and the individual's skin permeability. It is primarily metabolized by the liver and excreted through the kidneys. The absorption through the scalp is generally low, with minimal systemic effects when used topically as a shampoo. |
| suggested dosage | Apply to wet hair and scalp, lather, leave on for 2-5 minutes, rinse thoroughly. Frequency of application varies depending on the condition, but generally twice per week or as directed by a physician. |
| indications | Treatment of seborrheic dermatitis, tinea capitis (scalp ringworm), and other fungal scalp infections. |
| safety in pregnancy | Limited data on use during pregnancy. It's essential to consult a healthcare provider before using ketoconazole shampoo during pregnancy to discuss potential risks and benefits. Avoid use during the first trimester if possible. The risk of fetal harm from topical use is considered low. However, it is crucial to only use as prescribed by the doctor. |
| safety in breastfeeding | Limited data available. It is essential to consult a healthcare provider before using ketoconazole shampoo while breastfeeding to assess the potential risks to the infant. |
| side effects | | 1 | Skin irritation (itching, redness, burning) | | 2 | Hair loss (rare) | | 3 | Allergic reactions (rash, hives) | | 4 | Dryness of scalp | | 5 | Hair breakage (rare) |
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| alternatives | |
| contraindications | Known hypersensitivity or allergy to ketoconazole or any components of the shampoo. |
| interactions | Potentially interacts with certain medications, including but not limited to other antifungals, azole medications, and drugs metabolized by the liver. Always inform your doctor of all medications you are taking. |
| warnings and precautions | | 1 | Avoid contact with eyes. If contact occurs, rinse immediately with plenty of water. | | 2 | Do not use on broken skin. | | 3 | If symptoms worsen or do not improve after a few weeks of treatment, consult a physician. | | 4 | Use caution in patients with pre-existing skin conditions. | | 5 | Monitor for any signs of hypersensitivity reaction. | | 6 | Use only as directed. Do not increase dosage or frequency of use without consulting your doctor. |
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| additional informations | It's recommended to use a moisturizing conditioner after using ketoconazole shampoo to prevent dryness. Always follow the instructions on the product label. If you experience significant side effects, stop using the shampoo and seek medical attention immediately. |
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