| drug name | Lindane |
| classification | Insecticide, pediculicidal, scabicidal |
| pharmacokinetics | Lindane is rapidly absorbed through the skin and distributed throughout the body. It is metabolized in the liver and excreted in the urine. The half-life varies depending on the formulation and individual factors. |
| suggested dosage | **Use with extreme caution and only under the strict supervision of a physician.** Dosage and duration of treatment are highly variable and should be determined by a healthcare professional based on the specific condition, the severity of the infestation, and the patient's individual characteristics. *Self-treatment is strongly discouraged.* |
| indications | Lindane is primarily used to treat head lice (pediculosis capitis) and scabies. It is NOT a first-line treatment for these conditions and is often reserved for situations where other treatments are ineffective or inappropriate. Its use should be carefully considered due to its potential toxicity. |
| safety in pregnancy | Lindane is **contraindicated** during pregnancy. There is potential risk of harm to the developing fetus. Alternative treatments should be considered. |
| safety in breastfeeding | Lindane is **contraindicated** during breastfeeding. It can be transferred into breast milk and potentially harm the infant. Alternative treatments are necessary. |
| side effects | | 1 | Skin irritation (itching, redness, rash) | | 2 | Headache | | 3 | Dizziness | | 4 | Nausea | | 5 | Vomiting | | 6 | Seizures (rare but serious) | | 7 | Neurological effects (e.g., tremors, incoordination) | | 8 | Hepatic dysfunction (rare) | | 9 | Renal dysfunction (rare) |
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| alternatives | | 1 | | alternative drug | Permethrin | | class | Insecticide | | comment | Often preferred over lindane as a first-line treatment for lice and scabies due to a generally better safety profile. |
| | 2 | | | 3 | |
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| contraindications | | 1 | Known hypersensitivity to lindane or any of its components | | 2 | Severe liver or kidney disease | | 3 | History of seizures or neurological disorders | | 4 | Pregnancy and breastfeeding (absolute contraindications) |
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| interactions | | 1 | Potentially interacting with other medications (e.g., certain drugs affecting the liver or central nervous system). Consult a healthcare professional for possible drug interactions. |
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| warnings and precautions | | 1 | Use only as directed by a healthcare professional. Follow all instructions carefully. | | 2 | Avoid contact with eyes, mouth, and open wounds. | | 3 | Wear appropriate protective clothing during application. | | 4 | Wash hands thoroughly after application. | | 5 | Keep out of reach of children. | | 6 | Use the lowest effective dose for the shortest duration possible. | | 7 | Thoroughly monitor for any signs of adverse reactions. | | 8 | Monitor the patient closely for any signs of toxicity. |
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| additional information | | 1 | Lindane has a potential for cumulative toxicity, meaning repeated or prolonged use can increase the risk of adverse effects. | | 2 | Patients with a history of seizures or other neurological disorders should use extreme caution, with close medical monitoring, if prescribed Lindane. | | 3 | The specific dosage and application method for lindane will be determined by a healthcare professional. It is crucial to avoid self-treating. |
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| patient information | | age | 25 | | weight | 70 | | notes | The patient's age and weight are not factors in the specific dosage recommendations, but should be considered for overall health assessment |
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| important note | **This information is for educational purposes only and does not constitute medical advice.** Consult with a healthcare professional before using lindane or any other medication. |
