| name | Mupirocin ointment |
| classification | Topical antibacterial agent |
| pharmacokinetics | Mupirocin is a topical antibiotic that is primarily absorbed by the skin. It is not systemically absorbed to a significant degree, therefore systemic side effects are rare. The drug is rapidly inactivated by normal skin flora. No extensive data on pharmacokinetics in a 25-year-old male weighing 70 kg is available. |
| suggested dosage | Apply a thin layer of ointment to the affected area 2-3 times daily for 2-5 days, or as directed by a physician. The duration of treatment depends on the severity and response to therapy. Do not exceed the prescribed dosage. |
| indications | Mupirocin is primarily used for topical treatment of superficial skin infections, such as impetigo, folliculitis, and other skin conditions caused by susceptible bacteria. It's effective against Staphylococcus aureus and Streptococcus pyogenes. |
| safety in pregnancy | Limited data on pregnancy is available. While not expected to pose a major risk to the fetus, use during pregnancy is not routinely recommended without direct supervision by a healthcare professional. Consult a physician before use if pregnant or planning to become pregnant. |
| safety in breastfeeding | Mupirocin is likely safe to use during breastfeeding. The ointment is applied topically and not expected to significantly enter the systemic circulation, so concerns of adverse effects in the infant are low. However, consult with a physician or lactation consultant before using the medication during breastfeeding. |
| side effects | | 1 | Skin irritation | | 2 | Skin rash | | 3 | Burning sensation at application site | | 4 | Pain | | 5 | Pruritus(itching) |
|
| alternatives | |
| contraindications | | 1 | Hypersensitivity to mupirocin or other ingredients in the ointment | | 2 | Known skin reactions to the medication | | 3 | Use over large areas of skin for prolonged periods of time without professional supervision |
|
| interactions | Limited interactions are anticipated. If the patient is taking other medications, or has underlying medical conditions, consult a healthcare professional for possible drug interactions before using this medication. |
| warnings and precautions | | 1 | Avoid contact with eyes, mucous membranes, or open wounds. | | 2 | Keep the ointment away from children and pets. | | 3 | Wash hands thoroughly after application. | | 4 | Seek medical attention if symptoms worsen or do not improve after 2-3 days. | | 5 | Do not use this medication for treating infections not related to the skin. |
|
| additional informations | Mupirocin is effective against a range of bacterial species, but its effectiveness might be impacted by improper usage or lack of adequate treatment time. Mupirocin can be used to treat nasal colonization of Staphylococcus aureus to prevent the spread of infection but this use often requires consultation with healthcare provider. |
