| name | Prednisolone Topical Cream |
| classification | Corticosteroid, Topical |
| pharmacokinetics | Prednisolone, a glucocorticoid, is applied topically. Absorption into the systemic circulation is generally low but can vary depending on the concentration, site of application, and duration of treatment. Bioavailability is minimal. Metabolism is primarily hepatic. |
| suggested dosage | Dosage is highly dependent on the specific condition being treated. This information is not appropriate for self-treatment. A healthcare professional should assess the appropriate dosage and frequency. General guideline for topical corticosteroids is usually a thin film applied 1-2 times daily. |
| indications | Prednisolone topical cream is used to treat inflammatory skin conditions like eczema, dermatitis, contact dermatitis, and some skin infections. |
| safety in pregnancy | Limited data exists on use of topical prednisolone in pregnancy. Topical application is generally considered safe, however, consult with your physician to assess individual risk-benefit ratio. |
| safety in breastfeeding | Limited data exists regarding topical prednisolone use during breastfeeding. However, topical corticosteroids are generally considered safe if used as directed by a healthcare professional. Consult with your physician to discuss the risks and benefits. |
| side effects | Common topical side effects may include skin irritation, redness, dryness, and mild burning or itching. Rarely, more serious side effects like skin thinning, atrophy, or striae may occur with prolonged or high-dose use. |
| alternatives | | 1 | | alternative drug | Hydrocortisone topical cream | | notes | Often a first-line treatment for milder inflammatory skin conditions due to lower potential for side effects. |
| | 2 | | | 3 | |
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| contraindications | Known hypersensitivity to prednisolone or other corticosteroid preparations. Use with caution in patients with severe skin infections or conditions where systemic absorption may be problematic (e.g., extensive skin areas affected). |
| interactions | Concomitant use of other topical medications may modify the absorption or efficacy of prednisolone. Consult with your physician if using any other topical treatments, oral medications, or supplements. |
| warnings and precautions | Avoid contact with eyes. Do not apply occlusive dressings unless specifically directed. If symptoms worsen or persist, consult a physician. Do not use for prolonged periods without consulting your healthcare provider. Monitor for signs of systemic absorption. Consider other treatment options if systemic corticosteroids are deemed inappropriate. Do not use on open wounds or broken skin. |
| additional informations | Patient age and weight are not relevant factors in determining topical corticosteroid dosage. The key determinants are the specific condition being treated, severity, and location. This information is for educational purposes only and does not constitute medical advice. Consult a healthcare professional for personalized advice and treatment. |
| patient specific notes | A 25-year-old male weighing 70 kg is not a factor in determining topical corticosteroid dosage for a localized skin condition. |
