| drug name | Hydrocortisone Topical |
| classification | Topical Corticosteroid |
| pharmacokinetics | Hydrocortisone, when applied topically, is primarily absorbed by the skin. The degree of absorption depends on the formulation (e.g., ointment, cream, lotion), concentration, duration of application, and the health of the skin. Systemic absorption is generally minimal with proper use. Limited metabolism occurs in the skin, and the drug is largely excreted in the urine. |
| suggested dosage | Dosage is highly variable depending on the condition being treated. Consult a physician. General guidelines for topical hydrocortisone include applying a thin layer to the affected area 1-4 times daily. Do not exceed the recommended frequency or duration of use without medical supervision. A physician should determine the correct dosage and regimen. |
| indications | Hydrocortisone topical is used to treat various inflammatory skin conditions such as eczema, dermatitis, contact dermatitis, and psoriasis. It's also used for treating itching, redness, and swelling associated with these conditions. It can also be used to treat some skin infections. |
| safety in pregnancy | Hydrocortisone topical is generally considered safe during pregnancy when used appropriately and topically, with minimal systemic absorption. However, it is important to discuss use with a healthcare provider. |
| safety in breastfeeding | Hydrocortisone topical, with minimal systemic absorption, is generally considered safe during breastfeeding when used as directed. However, it's important to consult with a healthcare professional to discuss potential risks. |
| side effects | | 1 | Local skin reactions (e.g., burning, stinging, irritation, dryness, skin atrophy, striae, hypopigmentation) | | 2 | Systemic effects (although rare with topical use) - possible with high concentration, prolonged application, or large areas treated may include Cushing's syndrome symptoms (e.g., weight gain, mood changes), adrenal insufficiency | | 3 | Rare cases of hypersensitivity reactions (e.g., rash, itching, swelling). |
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| contraindications | | 1 | Known hypersensitivity or allergy to hydrocortisone or other topical corticosteroids. | | 2 | Active skin infections that are not fungal or viral in origin. (e.g. bacterial infections) - a physician should determine the appropriate medication | | 3 | Use over large areas of the body or prolonged use. |
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| interactions | Limited interactions are expected with topical hydrocortisone. However, concomitant use of other topical medications, particularly other anti-inflammatory agents or immunosuppressants, may need careful monitoring. Always inform your physician about all medications you are currently taking. |
| warnings and precautions | | 1 | Do not use over open wounds or broken skin unless directed by a physician. | | 2 | Avoid contact with the eyes, nose, or mouth. | | 3 | Do not use for longer than directed by a healthcare provider. | | 4 | If symptoms worsen or do not improve, discontinue use and consult a physician. | | 5 | Apply only to the affected area and avoid contact with healthy skin. |
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| additional informations | | 1 | Always follow your doctor's instructions for dosage and application. | | 2 | Patients with a history of skin conditions, immune disorders, or other medical problems should discuss use with a physician. | | 3 | The age and weight of the patient is not a factor for dosage of topical corticosteroids in this case. | | 4 | This information is for general knowledge and does not constitute medical advice. Always consult with a healthcare professional for personalized medical guidance. |
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