| name | Hydrocortisone |
| strength | 10 mg |
| classification | Glucocorticoid, Anti-inflammatory |
| pharmacokinetics | | absorption | Rapidly absorbed from skin, other sites, and IV. Bioavailability varies by route. | | distribution | Widely distributed, crosses placenta and breast milk. | | metabolism | Primarily metabolized in the liver, remainder excreted in urine and bile. | | excretion | Primarily in urine and bile. |
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| dosage forms | | 1 | | form | oral | | details | Dosage depends on indication, severity, and patient response. Consult physician. |
| | 2 | | form | topical | | details | Dosage depends on skin area and severity; follow product instructions. No single dosage universally applies. Consult physician. |
| | 3 | | form | intravenous | | details | Dosage determined and adjusted by physician based on individual response and medical condition. |
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| indications | | 1 | Allergic reactions | | 2 | Dermatologic diseases (eczema, dermatitis, psoriasis) | | 3 | Rheumatologic diseases | | 4 | Gastrointestinal disorders | | 5 | Autoimmune diseases | | 6 | Inflammatory conditions | | 7 | Adrenal insufficiency replacement therapy | | 8 | Poison ivy and similar reactions |
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| safety in pregnancy | Generally considered safe, but physician monitoring is crucial. |
| safety in breastfeeding | Potent drug. Limited clinical information on topical use. Use only when clinically necessary. |
| side effects | | 1 | | route | Systemic | | effects | | 1 | Fluid retention | | 2 | Mood changes | | 3 | Weight gain | | 4 | Osteoporosis | | 5 | Hypertension | | 6 | Cushing's syndrome (with long-term, high-dose use) | | 7 | Skin thinning (atrophy) | | 8 | Striae (stretch marks) | | 9 | Increased risk of infections | | 10 | Gastrointestinal upset |
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| | 2 | | route | Topical | | effects | | 1 | Skin irritation | | 2 | Burning | | 3 | Redness |
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| | 3 | | note | Systemic absorption from topical use can cause many of the same side effects as oral use. |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to hydrocortisone or other ingredients | | 2 | Severe fungal or bacterial skin infections (use with extreme caution) | | 3 | Active or suspected tuberculosis |
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| interactions | | 1 | Other corticosteroids | | 2 | Medications affecting liver function | | 3 | Nonsteroidal anti-inflammatory drugs (NSAIDs) |
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| warnings and precautions | | 1 | Long-term or high-dose use can cause serious side effects; monitor closely. | | 2 | Avoid abrupt discontinuation; taper dosage to avoid adrenal insufficiency. | | 3 | Use with caution in patients with pre-existing conditions (diabetes, hypertension, heart disease). | | 4 | Follow physician instructions. | | 5 | Report any concerning signs or symptoms. |
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| additional information | Available in various formulations (oral, topical, injectable). Physician determines specific formulation, route, and dosage. |
| important note | This information is for general knowledge only and does not constitute medical advice. Consult a healthcare professional for any health concerns or before starting any medication. |
