| name | Retinol |
| classification | Vitamin A, Retinoid |
| pharmacokinetics | | absorption | Retinol is absorbed from the small intestine, primarily by passive diffusion. Dietary fats enhance absorption. | | distribution | Retinol is transported in the blood bound to retinol-binding protein (RBP). | | metabolism | Metabolized primarily in the liver. The active form of retinol is then converted to retinal and retinoic acid. | | excretion | Excreted primarily via the bile in the feces. |
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| suggested dosage | | note | Dosage depends significantly on the form of retinol (e.g., retinol palmitate, oral retinol), its intended use (e.g., acne treatment, vitamin supplementation), and individual patient needs. This information is not a substitute for professional medical advice. Consult a doctor or pharmacist. | | typical for vitamin supplementation | Depending on the specific product, a daily dose of 5000-10000 IU is often recommended (consult a doctor). | | for acne treatment | The appropriate dosage for acne will vary based on severity. Consultation with a dermatologist is crucial. | | weight 70kg no specific indication | No specific dosage is readily available based solely on a patient's weight and age of 25 without a specific reason for needing retinol. A healthcare provider should determine the necessary dose. |
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| indications | | 1 | Vitamin A deficiency | | 2 | Acne treatment (often in combination with other medications) | | 3 | Maintenance of healthy vision and immune function | | 4 | Certain skin conditions | | 5 | Prophylaxis for certain diseases (with specific conditions) |
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| safety in pregnancy | Retinol use during pregnancy should be carefully considered and only under direct medical supervision. High doses of retinol may have adverse effects on the developing fetus, and can be teratogenic. Do not self-treat. |
| safety in breastfeeding | Limited information on retinol's safety during breastfeeding exists. It's best to consult with a healthcare professional regarding the potential risks and benefits before use. |
| side effects | | 1 | Headache | | 2 | Nausea | | 3 | Vomiting | | 4 | Dry mouth | | 5 | Dry skin | | 6 | Hair loss | | 7 | Liver damage (at high doses) | | 8 | Fatigue | | 9 | Bone pain | | 10 | Birth defects if used during pregnancy (at high doses) | | 11 | Skin irritation (during topical use) |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity or allergy to retinol or related retinoids | | 2 | Severe liver disease | | 3 | Pregnancy (except under strict medical supervision) | | 4 | Certain underlying health conditions (consult with doctor) |
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| interactions | | 1 | Certain medications (e.g., anticoagulants, some oral contraceptives) | | 2 | Alcohol (can exacerbate liver damage) | | 3 | Other vitamin supplements (potential interactions exist) |
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| warnings and precautions | | 1 | Never use higher than recommended doses of retinol without professional guidance. | | 2 | Retinol can cause skin irritation, especially when used topically. Apply sparingly. | | 3 | Monitor for any adverse effects like liver issues, headaches, or skin problems. | | 4 | Discuss any potential interactions with other medications or supplements. |
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| additional informations | | 1 | Retinol is available in various forms, including oral supplements, topical creams, and solutions. | | 2 | Retinol's effects can take time to manifest. | | 3 | It's essential to consult a healthcare professional for appropriate dosage and usage guidance, especially regarding pregnancy or pre-existing medical conditions. | | 4 | The information provided here is for general knowledge and does not constitute medical advice. |
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