| name | Fexofenadine |
| classification | Antihistamine, H1 receptor antagonist |
| pharmacokinetics | | absorption | Rapidly absorbed after oral administration, peak plasma concentrations typically reached within 1-2 hours. | | distribution | Widely distributed throughout the body, including the central nervous system. Fexofenadine is primarily metabolized in the liver. | | metabolism | Hepatic metabolism primarily through the cytochrome P450 system (CYP3A4). | | excretion | Primarily excreted in the urine as metabolites. The unchanged drug accounts for a small fraction of the total excretion. |
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| suggested dosage | | adult | 20 mg twice daily for most conditions. Higher dosages may be appropriate in some cases but are generally not necessary for a 25-year-old, 70 kg male. Consult a physician for specific dosage recommendations. | | pediatric | Dosage varies by age and weight. Consult a physician. |
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| indications | Relief of symptoms associated with allergic rhinitis (hay fever) and urticaria (hives). May also be used in the treatment of chronic idiopathic urticaria. |
| safety in pregnancy | Limited data available. Fexofenadine is generally considered safe during pregnancy but always consult with a healthcare professional regarding medication use during pregnancy. Risks and benefits should be carefully evaluated. |
| safety in breastfeeding | Fexofenadine is generally considered safe for use while breastfeeding but consult with a healthcare professional. |
| side effects | | 1 | Headache | | 2 | Dizziness | | 3 | Fatigue | | 4 | Nausea | | 5 | Vomiting | | 6 | Diarrhea | | 7 | Constipation | | 8 | Dry mouth | | 9 | Somnolence (sleepiness) | | 10 | Rash | | 11 | Pruritus (itching) |
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| alternatives | |
| contraindications | Known hypersensitivity to fexofenadine or any of its components. Use with caution in patients with severe hepatic impairment. |
| interactions | | 1 | Specific interactions may occur with certain drugs (e.g., medications that affect liver enzymes). Always inform your doctor about all medications you are currently taking. | | 2 | May potentiate the effects of other CNS depressants |
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| warnings and precautions | Caution in patients with kidney disease, though generally well-tolerated. Patients with liver impairment should use with caution and under medical supervision. |
| additional informations | | important notes | Fexofenadine is generally well-tolerated and safe, but individual responses may vary. Always consult a doctor before starting any new medication. | | overdose information | Consult a physician or seek emergency medical attention if an overdose is suspected. Symptoms might include those listed under side effects, but more severe. |
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