| name | Loratadine |
| Classification | Antihistamine, H1 receptor antagonist |
| Pharmacokinetics | Loratadine is well absorbed from the gastrointestinal tract. Peak plasma concentrations are typically reached within 1-2 hours. It is highly protein-bound (90-95%). The primary metabolic pathway involves hepatic cytochrome P450 enzymes (CYP3A4). The drug has a long half-life (8-15 hours) allowing for once-a-day dosing. Elimination is primarily via the liver. |
| suggested dosage | | adult (including patients aged 12 years and older) | | allergic rhinitis | 10 mg once daily | | other indications | 10 mg once daily | | children | 10 mg once daily for patients 12 years and older; doses for children under 12 should be determined by a doctor | | weight specific note | No dosage adjustments are typically needed for patients weighing 70kg. |
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| indications | | 1 | Seasonal allergic rhinitis | | 2 | Chronic idiopathic urticaria | | 3 | Other allergic skin conditions | | 4 | Chronic hives | | 5 | Allergic conjunctivitis |
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| safety in pregnancy | Loratadine is generally considered safe for use during pregnancy, but only use as directed by a doctor. Adequate studies are lacking to support safe use of loratadine in pregnancy. |
| safety in breastfeeding | Loratadine is considered safe for use during breastfeeding. However, consult a doctor about risks and benefits. |
| side effects | | 1 | Headache | | 2 | Dizziness | | 3 | Fatigue | | 4 | Dry mouth | | 5 | Nausea | | 6 | Vomiting | | 7 | Constipation | | 8 | Diarrhea | | 9 | Rarely serious allergic reactions or other adverse effects | | 10 | Note: Always report unusual or concerning symptoms to your doctor. |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to Loratadine or other ingredients in the product | | 2 | Severe liver dysfunction |
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| interactions | Loratadine is generally considered to have few clinically significant drug interactions. However, interaction with other medications or supplements should be discussed with a healthcare provider. |
| warnings and precautions | | 1 | Use with caution in patients with pre-existing liver disease. | | 2 | Avoid alcohol and other CNS depressants when taking Loratadine. | | 3 | Not recommended for use in children under 2 years of age without specific doctor's guidance. | | 4 | If symptoms worsen or do not improve after a reasonable period, consult a doctor. |
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| additional information | Loratadine is available as oral tablets, liquid, and other dosage forms. It is typically very well tolerated; however, specific cautions or concerns should always be addressed with your doctor. If you experience any concerning side effects, contact a doctor right away. |
| patient specific note | As a 25-year-old male weighing 70kg, the standard dose of loratadine should be appropriate, but adherence to prescribed dosages and seeking professional guidance in case of specific conditions or concerns is crucial. |
