| name | Loratadine |
| classification | First-generation antihistamine (H1-receptor antagonist) |
| pharmacokinetics | Loratadine is well absorbed orally, with peak plasma concentrations typically achieved within 1-2 hours. It has a long half-life, allowing for once-daily dosing. It is primarily metabolized in the liver. Excretion is primarily in the urine. |
| suggested dosage | | adult | 10 mg once daily | | notes | No specific adjustments are generally needed for males aged 25 with a weight of 70 kg. Follow the label directions. |
|
| indications | | 1 | Seasonal allergic rhinitis | | 2 | Perennial allergic rhinitis | | 3 | Urticaria (hives) | | 4 | Allergic conjunctivitis |
|
| safety in pregnancy | Limited data; generally considered safe. Consult a healthcare professional. |
| safety in breastfeeding | Generally considered safe; however, more research on long-term effects on infants is needed. Consult a physician. |
| side effects | | 1 | Headache | | 2 | Drowsiness | | 3 | Dry mouth | | 4 | Nausea | | 5 | Vomiting | | 6 | Diarrhea |
|
| alternatives | |
| contraindications | | 1 | Known hypersensitivity to loratadine or other ingredients | | 2 | Severe hepatic impairment |
|
| interactions | | 1 | May interact with other medications affecting liver or kidney function. | | 2 | No significant interactions with food. |
|
| warnings and precautions | | 1 | May cause drowsiness, especially when taken with other sedating medications. Avoid hazardous activities. | | 2 | Consult a doctor about pre-existing conditions or ongoing medications. |
|
| additional information | | 1 | Available as both generic and brand-name preparations | | 2 | Over-the-counter availability |
|
| dosage form | Tablet |
